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Research Interests

The Storey Lab studies the biochemical adaptations and molecular mechanisms that allow animals to adapt to and endure severe environmental stresses such as the deep cold, oxygen deprivation, and desiccation. 

Positions Available

New projects are available for Graduate students and Honours students. For a more detailed description of the projects currently available for Graduate and Honours students visit the Opportunities page. 

Contact Information

Email: Kenneth_StoreyATcarleton.ca
Email: Jan_Storey@carleton.ca

Telephone: +1 (613) 520-2600 x3678
Fax: +1 (613) 520-3749

Featured New Publications 

Comparative enzymology – new insights from studies of an “old” enzyme, lactate dehydrogenase. Storey, K.B. 2016. Comp. Biochem. Physiol. B, 199, 13–20.  PMID: 26688543

Lessons from mammalian hibernator: molecular insights into striated muscle plasticity and remodeling. Tessier, S.N. and Storey, K.B. 2016. BioMol. Concepts 7(2), 69-92. PMID: 26982616

Life in the cold: links between mammalian hibernation and longevity. Wu, C.-W. and Storey K.B. 2016. Biomol. Concepts 7(1): 41-52. PMID: 26820181

Analysis of microRNA expression during the torpor-arousal cycle of a mammalian hibernator, the 13-lined ground squirrel. Wu, C.-W., Biggar, K.K., Luu, B.E., Szereswewski, K.E. and Storey, K.B. 2016. Physiol. Genomics 48(6):388-396. PMID: 27084747

 The role of DNA methylation during anoxia tolerance in a freshwater turtle (Trachemys scripta elegans). Wijenayake, S. and Storey, K.B. 2016. J. Comp. Physiol. B 186, 333-342. PMID: 26843075

The hibernating South American marsupial, Dromiciops gliroides, displays torpor-sensitive microRNA expression patterns. Sci. Rep. 6: 24627. Hadj-Moussa, H., Moggridge, J.A., Luu, B.E., Quintero-Galvis, J.F., Gaitán-Espitia, J.D., Nespolo, R.F. and Storey, K.B. 2016.   PMID: 27090740

Native denaturation differential scanning fluorometry: determining the effect of urea using a quantitative real-time thermocycler. Childers, C.L., Green, S.R., Dawson, N.J. and Storey, K.B. 2016. Anal. Biochem. 508, 114-117.   PMID: 27296634

A hydrogen peroxide safety valve: the reversible phosphorylation of catalase from the freeze tolerant North American wood frog, Rana sylvatica. Dawson, N.J. and Storey, K.B. 2016. Biochim. Biophys. Acta 1860, 476-485.  PMID: 26691137

Turn down genes for WAT? Activation of anti-apoptotic pathways protects white adipose tissue in metabolically depressed thirteen-lined ground squirrels. Logan, S.M., Luu, B.E. and Storey, K.B. 2016.  Mol. Cell. Biochem. 416:47–62. PMID: 27032768

Expression of nuclear factor of activated T cells (NFAT) and downstream muscle-specific proteins in ground squirrel skeletal and heart muscle during hibernation. Zhang, Y. and Storey, K.B. 2016. Mol. Cell. Biochem. 412(1), 27-40. PMID: 26597853

 

Special LEMUR Series:  Torpor in a Primate

The gray mouse lemur: a model for studies of primate metabolic rate depression. Storey, K.B. 2015. Genomics Proteomics Bioinformatics. 13, 77–80. PMID: 26102318

Primate torpor: Regulation of stress-activated protein kinases during daily torpor in the gray mouse lemur, Microcebus murinus. Biggar, K.K., Wu, C.-W., Tessier, S.N., Zhang, J., Pifferi, F., Perret, M. and Storey. K.B. 2015. Genomics Proteomics Bioinformatics. 13, 81–90. PMID: 26093282

Regulation of the PI3K/AKT pathway and fuel utilization during primate torpor in the gray mouse lemur, Microcebus murinus. Tessier, S.N., Zhang, J., Biggar, K.K., Wu, C.-W., Pifferi, F., Perret, M. and Storey, K.B. 2015. Genomics Proteomics Bioinformatics. 13, 91–102.   PMID: 26092184

Regulation of torpor in the gray mouse lemur: transcriptional and translational controls and role of AMPK signaling. Zhang, J., Tessier, S.N., Biggar, K.K., Wu, C.-W., Pifferi, F., Perret, M. and Storey, K.B. 2015. Genomics Proteomics Bioinformatics. 13, 103–110.  PMID: 26092186

Modulation of gene expression in key survival pathways during torpor in the gray mouse lemur, Microcebus murinus. Biggar. K.K., Wu, C.-W., Tessier, S.N., Zhang, J., Pifferi, F., Perret, M. and Storey, K.B. 2015. Genomics Proteomics Bioinformatics. 13, 111–118. PMID: 26093281

Induction of antioxidant and heat shock protein responses during torpor in the mouse lemur, Microcebus murinus. Wu, C.-W., Biggar, K.K., Tessier, S.N., Zhang, J., Pifferi, F., Perret, M. and Storey, K.B. 2015. Genomics Proteomics Bioinformatics. 13, 119–126.  PMID: 26092183

Cytokine and antioxidant regulation in the intestine of the gray mouse lemur (Microcebus murinus) during torpor. Tessier, S.N., Katzenback, B.A., Pifferi, F., Perret, M. and Storey, K.B. 2015. Genomics Proteomics Bioinformatics. 13, 127–135. PMID: 26092185